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The Hard Reboot - yohimbine + ginseng

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  • The Hard Reboot - yohimbine + ginseng

    After a fair amount of research, it has come to my attention that the possibility is there to do what I would like to call the "Hard Reboot". It appears that porn-induced erectile dysfunction has a significant correlation with overstimulating dopamine receptors. What I didn't realize previously is that yohimbine appears to be effective in reversing erectile dysfunction due to the fact that yohimbine is a dopamine antagonist.1 This means that the yohimbine bonds with dopamine receptors and blocks dopamine from reaching the receptors; thereby denying the dopamine response. The brain responds to this reduction in the dopamine response by growing new dopamine receptors and producing more dopamine.2 Dopamine antagonists are typically used in treating schizophrenia, in the attempt to grow these new receptors so that the dopamine produced in the schizophrenic's mind can be handled more effectively.

    Given that yohimbine will be blocking the receptors, the other aspect of the dopamine response is the produced dopamine. This is where the ginseng comes into play. Ginseng also effects dopamine, but it does so in a different way. "[I]t has been reported that ginsenosides Rb1, Rg1, Rc and Re inhibited tyrosine hydroxylse activity and exhibited anti-dopaminergic action since they reduced the availability of dopamine at presynaptic dopamine receptors."3 It appears that ginseng indirectly effects the dopamine before the dopamine travels through the synapse and to the receptors. So in this way (some of) the dopamine that would otherwise connect to any new receptors would be stopped before it had the chance to do so. Combined with the dopamine antagonist, the shortage of dopamine is going to stimulate more new growth of receptors.

    It is appropriate to mention that dopamine regulates prolactin in something of an inverse fashion; the more dopamine there is, the less prolactin is produced; while the less dopamine there is, the more prolactin is produced. So inducing such a dopamine shortage runs the risk to an increase in prolactin. However, ginseng is amazing in its ability to limit prolactin while simultaneously limiting dopamine.4 I have yet to find anything else that has that capacity, despite some online claims that maca can do this.

    Smoking obviously ruins anything good with respect to erectile fuction, but as it relates to dopamine it produces a dopaminergic respone. This could at the very least slow down any reboot; it may even make it worse if enough cigarettes are smoked. Yet ginseng manages to curtail the dopamine response in smoking as well. So if one is going to engage in smoking while performing a Hard Reboot, the effects will be dulled unless the smoker decides to smoke more in order to counterbalance the diminished dopamine stimulation. In other words, a Hard Reboot would be a great time to quit smoking since major withdrawal effects would be felt anyway. As a side note, there may be some promise in using the Sinclair Method for both smoking and porn (perhaps simultaneously), but that seems dangerous.

    The effects of reducing the dopamine response by such a large amount so quickly is going to have a shocking effect on an individual: so if one is to engage in it at all he must at least be in good enough physical shape. The dosage of yohimbine doesn't seem to vary by much, but anything between 15mg to 30mg divided into three doses per day over a course of ten weeks may be safe.5 As for ginseng, it appears that 1-2 grams per day for three months is safe.6 Yet studies related to erectile dysfunction and ginseng have taken place where 3000mg per day were used for 12 weeks.7

    In conclusion, the Hard Reboot is an attempt to increase the effectiveness of a reboot. It also appears that there is a correlation between social dominance and an increased dopamine response, so increasing the amount dopamine receptors may lead to a more 'alpha' state of mind.8 Ideally the Hard Reboot will be done in conjunction with exercise and a diet which promotes dopamine receptor growh, thereby maximizing the amount of dopamine one can handle after the reboot is complete. I present this in the attempt to get some feedback and criticism. I am going to experiment with this when the time comes, which is in about three weeks. A log will be kept on the forum for those who are interested.
    williammeasure
    Junior Member
    Last edited by williammeasure; 11-19-2012, 07:31 PM.

  • #2
    interesting, i'll read your log. i don't know much about supplements (i'm a simple man drinking his simple green tea, honey and lemon XD) but i did a quick google of "yohimbine" and it seems that its banned in australia.

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    • #3
      FWIW I couldn't tolerate yohimbe. It did give me raging boners, but along with it came the sensation I had just consumed two gallons of coffee. I quit it almost immediately.

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      • #4
        Originally posted by bautista19 View Post
        FWIW I couldn't tolerate yohimbe. It did give me raging boners, but along with it came the sensation I had just consumed two gallons of coffee. I quit it almost immediately.
        Do you recall what your typical dosage was?

        After looking more into this, it seems that the increased dopamine being produced after the antagonist takes effect results in an increase in norepinephrine.1 This may be the "two gallons of coffee" effect you're referring to. Personally, I recall the times I quit smoking cold turkey and I must say that I could describe the feeling in a similar way. So I continued to look for a way to reduce norepinephrine as well and stumbled upon another ED study using l-arginine and proanthocyanidins which apparently does just that.

        "After 1 month of treatment with L-arginine, a statistically nonsignificant number of 2 patients (5%) experienced a normal erection. Treatment with a combination of L-arginine and Pycnogenol for the following month increased the number of men with restored sexual ability to 80%. Finally, after the third month of treatment, 92.5% of the men experienced a normal erection."2

        So it seems that reducing the amount of dopamine is going to produce an increase in norephinephrine, which in turn can be reduced by churning out nitric oxide using l-arginine and proanthocyanidins. Nitric oxide also relaxes smooth muscle, which may be another reason why the l-arginine and proanthocyanidins are so effective.3

        In this case it appears to me that a Hard Reboot should also contain l-arginine and proanthocyanidins. Norepinephrine receptors would grow when there would be a 'deficiency' brought on by the nitric oxide; which in turn could help with premature ejaculation, since a norephinephrine spike is an orgasm trigger. 4

        The dosage of each ingredient is important, but perhaps not so important as to not give this a shot. It's not something anyone would want to take forever, but it seems that most of these ingredients are safe for roughly three months, which corresponds to a nofap or most of a reboot.

        So, in total there would be four ingredients to a Hard Reboot:

        yohimbine - dopamine antagonist
        ginseng (red) - dopamine and prolactin reducer
        l-arginine - supplement for the precursor to nitric oxide
        proanthocyanidins (found in maritime pine bark or grape seed extract) - supplements the production of nitric oxide 5


        In short:

        dopamine receptor increase (dopamine decrease) - improves response to dopamine; more reward from social associations.
        prolactin decrease - improves refractory period
        norepinephrine decrease - reduces "fight or flight" response; improves time of ejaculation
        nitric oxide - decreases norepinephrine, relaxes smooth muscle

        I won't have the chance to try a Hard Reboot for a couple of weeks, but after continually turning up benefits from all these different directions, I'm starting to become convinced that this could work best in this particular combination, even if one decides not to use the yohimbine. They all seem to work together and I have yet to find anything significant yet with regard to combining these supplements that could have bad results per se. If anyone has more more to add on that I would love to see it.

        One more thing, the norepinephrine decrease may make the Hard Reboot easier.
        williammeasure
        Junior Member
        Last edited by williammeasure; 11-21-2012, 07:47 PM.

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        • #5
          Im interested in the log.I wanted to try yohimbine for shredding up,but Dont like the idead of increased prolactin.Ive always had borderline high prolactin,currecntly supplement with l-dopa CArboxy to keep it in check.

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          • #6
            Effect of yohimbine hydrochloride on serum prol... [Am J Vet Res. 1986] - PubMed - NCBI Doesnt raise prolactin orally.Thank god.

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