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~Important~ Drugs that may cause E.D - Read this before posting a new thread!
VERY IMPORTANT :: Always discuss this information with your Doctor, do not attempt to just stop taking the drug without letting your doc know - and always examine other aspects of your lifestyle as well! Taking one of these drugs does NOT by any means guarantee the said side-effects - and indeed, you may achieve more therapeutic effects by simply lowering the dose, and thus achieving a happy balance while treating your condition! :: VERY IMPORTANT ::
This information does not serve to replace a medical doctor's decisions or advice - it simply should be looked at but not considered as the absolute cause of one's issues - it is for information purposes ONLY!
To make sure this doesn't apply to you, and you may still mention it in the thread so we can figure out the contributing factors.
Now fellas, there are many drugs that may cause erectile dysfunction, I am to briefly go over the common ones and why they do so - and offer a mirror on some of the excerpts/summary's.
There are so many parallel's and correlations that can be made - but only some of them remain relevant...and indeed, not ALL who use these drugs will get E.D - but it certainly serves as a risk factor.
Let's start with one of the most common. {Medicinal Causes of ERECTILE DYSFUNCTION}
1.) Anti-Depressant Drugs; Mainly of the SSRI class (lexapro,zoloft,paxil,luvox,celexa etc) - these drugs may raise prolactin, lower testosterone, cause cortisol excess and cause erectile issues, including anywhere from a reduced E.Q (erection quality) to total penile nerve non-responsivity. They may also cause delayed ejaculation, lack of orgasms, increased refractory period (increased wait time between getting a new erection/ejac) and a multitude of cognitive and emotional issues - including a dampening of emotions and the inability to feel love.
The reason for all of the above - are that serotonin directly dampens the emotional and sexual zones of the brain by acting to oppose dopamine, glutamate and other excitory factors - as well as causing oxytocinergic malfunction....something dopamine and other neuro-transmitters tend to increase...!
It's also the flood of serotonin in the synapse, that causes this dysfunction, due to a local overload, and lack of targeting other area's simultaneously, in terms of the dopamine transporter never affected.
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Essentially and simply put, these SSRI anti-depressant drugs dull out your nerves and subject one to CONTRACTION (vasoconstriction) - the worst possible combination of effects for sexual function.
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Here is a completed "mega-article" on PSSD/Anti-Depressant induced sexual dysfunction - Insights into PSSD ~ A Collection of Data & Detailed Analysis of the Etiology and Pathology of Post-SSRI-Sexual Dysfunction as well as Possible Novel Treatment Approaches
NOTE: Wellbutrin and norepinephrine and / or dopamine reuptake inhibitor anti-depressants cause less sexual dysfunction, on average - but they may also cause vasoconstriction - however, they have a higher tendency to increase libido as opposed to decrease it - the vasoconstrictive effects of wellbutrin can be easily eliminated by adding an alpha-1-blocker such as doxasozin or prasozin, or trazodone.
2.) BETA-BLOCKERS; A blood pressure pill, with anti-sympathetic (nervous system depressing) effects - shown in the following study to cause a decrease in testosterone and in general sexual function ~ generally propanolol (Inderal,Cipral) is the worst. The side-effects can be reduced by ********* supplements but this may also reduce the positive effects on blood pressure by these drugs .
3.) Histamine H(2)Antagonists; stomach acid pills; such as tagamet (cimetidine) and Zantac (ranitidine) - these drugs are highly psychoactive and may also produce psychotic side-effects and unchecked hostility - they do this through a similar mechanism as betablockers but carry an even higher incidence of sexual side-effects (!) that may also be more broad scale and definitive. These drugs may also diminish -testosterone- levels, cause cognitive deficits and erratic personalities to spring up - they also may cause disturbing types of anxiety and even paranoia.
4.) Bendadryl, anticholinergics, antihistamines (H1)....::....
I place these all into the same category because their effects are interexchangeable, and often simultaneous - both anticholinergic drugs (like benzotropine,used for antipsychotic side-effects, tremors, and parkinson's disease) and histamine H1 blockers, like promethazine, and benadryl, have dual mode of actions.....both of them decrease histamine, and both of them one way or another will decrease or inhibit the effects of acetylcholine - both of which are generally undesirable effects - especially in terms of central non-contact erections....
In addition, these drugs can make one very tired, and this certainly can kill the mood if you are in a sedated state!
So by both a phsyiological and PSYCHOLOGICAL / Mental , mechanism, these drugs can certainly cause Erectile dysfunction !
5.) AntiPsychotic drugs; they all induce prolactin release and in some cases, adrenaline issues as well - they all have an antihistamine property, which makes them terribly sedating, and , as said above, are commonly given with anticholinergics to stop the tremors they cause - compounding the issue. (1) (2)
6.)CORTICOSTEROIDS; Inhalers, oral corticosteroids for inflammation etc..these all can lower testosterone, induce estrogen issues and cause muscle catabolism as well as fat gain, especially in the abdominal regions - compounding the issue.
7.) BENZO's ; Can induce loss of libido, and can decrease testosterone levels when given *over time*...(!)
This is because they induce CNS depression and can tell the brain to reduce sex hormone production over time - and also, GABA directly opposes glutamate, and you need some glutamate for libido and nitric oxide production. (!) (!)
8.) Finasteride, Propecia, prostate/hairloss drugs...
These drugs may induce estrogen dominance, prolactin issues, anxiety, depression (!) (!) and cause a general loss of libido, personality changes, and very hard - to - treat erectile dysfunction.
This information does not serve to replace a medical doctor's decisions or advice - it simply should be looked at but not considered as the absolute cause of one's issues - it is for information purposes ONLY!
To make sure this doesn't apply to you, and you may still mention it in the thread so we can figure out the contributing factors.
Now fellas, there are many drugs that may cause erectile dysfunction, I am to briefly go over the common ones and why they do so - and offer a mirror on some of the excerpts/summary's.
There are so many parallel's and correlations that can be made - but only some of them remain relevant...and indeed, not ALL who use these drugs will get E.D - but it certainly serves as a risk factor.
Let's start with one of the most common. {Medicinal Causes of ERECTILE DYSFUNCTION}
1.) Anti-Depressant Drugs; Mainly of the SSRI class (lexapro,zoloft,paxil,luvox,celexa etc) - these drugs may raise prolactin, lower testosterone, cause cortisol excess and cause erectile issues, including anywhere from a reduced E.Q (erection quality) to total penile nerve non-responsivity. They may also cause delayed ejaculation, lack of orgasms, increased refractory period (increased wait time between getting a new erection/ejac) and a multitude of cognitive and emotional issues - including a dampening of emotions and the inability to feel love.
The reason for all of the above - are that serotonin directly dampens the emotional and sexual zones of the brain by acting to oppose dopamine, glutamate and other excitory factors - as well as causing oxytocinergic malfunction....something dopamine and other neuro-transmitters tend to increase...!
It's also the flood of serotonin in the synapse, that causes this dysfunction, due to a local overload, and lack of targeting other area's simultaneously, in terms of the dopamine transporter never affected.
::::::::::............................................. ....................::::::::::
.....................................:::::::::.......................................
Essentially and simply put, these SSRI anti-depressant drugs dull out your nerves and subject one to CONTRACTION (vasoconstriction) - the worst possible combination of effects for sexual function.
::::::::::............................................. ....................::::::::::
.....................................:::::::::.......................................
Here is a completed "mega-article" on PSSD/Anti-Depressant induced sexual dysfunction - Insights into PSSD ~ A Collection of Data & Detailed Analysis of the Etiology and Pathology of Post-SSRI-Sexual Dysfunction as well as Possible Novel Treatment Approaches
NOTE: Wellbutrin and norepinephrine and / or dopamine reuptake inhibitor anti-depressants cause less sexual dysfunction, on average - but they may also cause vasoconstriction - however, they have a higher tendency to increase libido as opposed to decrease it - the vasoconstrictive effects of wellbutrin can be easily eliminated by adding an alpha-1-blocker such as doxasozin or prasozin, or trazodone.
2.) BETA-BLOCKERS; A blood pressure pill, with anti-sympathetic (nervous system depressing) effects - shown in the following study to cause a decrease in testosterone and in general sexual function ~ generally propanolol (Inderal,Cipral) is the worst. The side-effects can be reduced by ********* supplements but this may also reduce the positive effects on blood pressure by these drugs .
3.) Histamine H(2)Antagonists; stomach acid pills; such as tagamet (cimetidine) and Zantac (ranitidine) - these drugs are highly psychoactive and may also produce psychotic side-effects and unchecked hostility - they do this through a similar mechanism as betablockers but carry an even higher incidence of sexual side-effects (!) that may also be more broad scale and definitive. These drugs may also diminish -testosterone- levels, cause cognitive deficits and erratic personalities to spring up - they also may cause disturbing types of anxiety and even paranoia.
4.) Bendadryl, anticholinergics, antihistamines (H1)....::....
I place these all into the same category because their effects are interexchangeable, and often simultaneous - both anticholinergic drugs (like benzotropine,used for antipsychotic side-effects, tremors, and parkinson's disease) and histamine H1 blockers, like promethazine, and benadryl, have dual mode of actions.....both of them decrease histamine, and both of them one way or another will decrease or inhibit the effects of acetylcholine - both of which are generally undesirable effects - especially in terms of central non-contact erections....
In addition, these drugs can make one very tired, and this certainly can kill the mood if you are in a sedated state!
So by both a phsyiological and PSYCHOLOGICAL / Mental , mechanism, these drugs can certainly cause Erectile dysfunction !
5.) AntiPsychotic drugs; they all induce prolactin release and in some cases, adrenaline issues as well - they all have an antihistamine property, which makes them terribly sedating, and , as said above, are commonly given with anticholinergics to stop the tremors they cause - compounding the issue. (1) (2)
6.)CORTICOSTEROIDS; Inhalers, oral corticosteroids for inflammation etc..these all can lower testosterone, induce estrogen issues and cause muscle catabolism as well as fat gain, especially in the abdominal regions - compounding the issue.
7.) BENZO's ; Can induce loss of libido, and can decrease testosterone levels when given *over time*...(!)
This is because they induce CNS depression and can tell the brain to reduce sex hormone production over time - and also, GABA directly opposes glutamate, and you need some glutamate for libido and nitric oxide production. (!) (!)
8.) Finasteride, Propecia, prostate/hairloss drugs...
These drugs may induce estrogen dominance, prolactin issues, anxiety, depression (!) (!) and cause a general loss of libido, personality changes, and very hard - to - treat erectile dysfunction.
Admin of the Month Dec 2014
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