Guaifenesin(Mucinex,robitussin) help premature ejaculation?

[db1525 Junior Member Find all posts View Profile Close db1525]

I am curious if anybody has experienced this? I was having a cold for the past week and a half and I decided to use some over the counter medicine, mucinex(the kind with just guaifenesin), to clear up my sinuses. I noticed that I was able to last significantly longer than usual.


I consistenly do the kegels/reverse and learning to relax the proper areas etc., which have benefited to a certain degree. But these times after starting the guaifenesin and relaxing during, it was almost like having to focus on making it happen at the end.


I checked google to see any connections. I found some instances of people noting this from taking the guaifenesin, but a lot of them were taking combo medications that had the guaifenesin either mixed with dextromethorphan or pseudoephedrine. Both I read can affect orgasm/ejaculation. One or two noted that they were taking straight guaifenesin.


This website, Use of guaifenesin in the treatment of urologic disorders - Bush, Irving M., talks about guaifenesin potentially being used for urogenital problems including prostatitis and decreased liquefaction of semen among other things. Both things that I have suspected to be a problem for me, especially the decreased liquefaction of semen. I noticed that it often comes out yellow and in clumps. All doctors I consulted have tested me as normal in terms of having no bacterial infection with no swelling etc. even with the symptoms that I tell them.


Also guaifenesin seems to be used for male fertility treatments to thin out the semen.


So my assumption is that maybe some cases of premature ejaculation are caused by some type of either lymph, mucus, or semen stagnation within the pelvic region causing some irritation of the nerves in that area, making them fire improperly. Which would make sense if the guaifenesin helps get rid of this congestion.


Also according to, The Role of Guaifenesin in Fibromyalgia., there seems to be a skeletal muscle relaxing property that is believed to cause the mucus releasing effect of the compound. It is significant in higher doses, so much as to be used as a horse tranquilizer in veterinary situations. So this may be what was causing the benefit to the premature ejaculation. Although if this was the primary cause, I feel like it won't be hitting the root of the problem that i'm looking for.


It seems safe definitely in the short term, likely in the long term as well. It is used pretty liberally for colds and the side effect sheet didn't seem too terrible. There are people using it in quite significant amounts over the regular dosage and daily for long periods of time to treat fibromyalgia. Also the compound was originally isolated from the wood of the guaiac tree, so it at least exists in nature and has historical use by native americans as a general remedy.


I plan to keep testing this past my cold to see if it is just a fluke. Has anyone experienced this effect with guaifenesin before?


Or is anyone with some similar symptoms interested in testing this and posting their results?

[no minute man Member Find all posts View Profile Close no minute man]

That's really interesting. Its definitely the first i've heard of it. I can relate to the reduced liquefaction of semen, although i've never thought there could be a link to me pre-e.

Did this happen consistently while you were taking it or just once?

[no minute man Member Find all posts View Profile Close no minute man]

BTW, yes, i will try it and let you know what happens

[no minute man Member Find all posts View Profile Close no minute man]

Did you just take a normal dose? And then, how long afterwards was it before you had the increased stamina?

[someone_like_u Retired ModeratorPEGym Hero Find all posts View Profile Close someone_like_u]

Also guaifenesin seems to be used for male fertility treatments to thin out the semen.

It also helps in women with thinning out cervical mucus while trying to conceive. And yes, I have noticed a difference in my own cervical mucus while taking meds. with guaifenesin.

[db1525 Junior Member Find all posts View Profile Close db1525]

I took it for a day or two before I tried. Those 2 days I took the 12 hour time release mucinex(guaifenesin only). Then I went at it at some point on the second day. The days after that I took irregularly 400mg generic instant release guaifenesin tablets once or twice a day. Maybe 3 days after the first time, I tried 400 mg like 30min-hr before going at it again. This was the only medication I was taking at that time. Both times results were similar in terms of being able to last longer, also I feel like the semen was thinned a bit the second time. But of course it's only two times so far.

So i'm not sure if it is one of those things that you can take like an hour before and it will work. It may have been that the couple days before I ejaculated, the guaifenesin was helping clear some stuff out.

I would test it a couple times a day, but I limit the amount of ejaculations I have to kind of rest the nerves.

But yeah, i'd love to hear your results

I did read about the cervical mucus thinning. So it definitely does seem to at least affect the reproductive system and not just the throat and sinuses like it's advertised for.

[Georgasm Junior Member Find all posts View Profile Close Georgasm]

So after googling "Mucinex and ejaculation", I came across a few stories and experiences that mentioned delayed ejaculation being a possible side effect of the congestion medicine. I have been reading some threads on this forum for a few weeks and finally decided to join after reading this post. I'm actually currently sick and taking Mucinex. I have no desire to masturbate or have sex right now but that's probably because I am sick. However, I would love to try this out and see how it goes when I feel better. If it works, it would be much safer than SSRIs or other pills although I do not know the side effects of long term use of Mucinex. I will get back to y'all ASAP.

[JamesMonroe Senior Member Find all posts View Profile Close JamesMonroe]

Hello everybody I haven’t been here for a while but I noticed I also took 1 pill of the 12 hour slow release Mucinex with only that guaifenesin ingredient and I definitely noticed I lasted longer and didn’t get an erection right away like usual. I will test it out with 2 pills for you guys and report back. Hope everyone’s doing good. If you are not taking the extra strength pills and you are only taking the regular pills you can take one to two pills.